2025’s Best-Performing Stocks – Top 10 High-Growth Stocks

Introduction:

The S&P 500 has had an impressive start to 2025 after two years of strong performance. Investors are optimistic that the bullish trend will continue. Even within the first month, some stocks have shown remarkable gains. The leading performers come from various sectors, including health care, artificial intelligence, and nuclear energy. Below is a list of the top-performing stocks of 2025, trading on major U.S. exchanges with a market capitalization of at least $1 billion.

Summary

1. FuboTV Inc. (FUBO)
2. Oklo Inc. (OKLO)
3. Akero Therapeutics Inc. (AKRO)
4. H&E Equipment Services Inc. (HEES)
5. OppFi Inc. (OPFI)
6. Agilon Health Inc. (AGL)
7. Tempus AI Inc. (TEM)
8. Grail Inc. (GRAL)
9. Exodus Movement Inc. (EXOD)
10. Inari Medical Inc. (NARI)

1. FuboTV Inc. (FUBO)

FuboTV is a sports-centric live TV streaming service. Despite struggling in recent years, trading at just $1.30 at the start of 2025, the stock skyrocketed after a major merger announcement with Walt Disney Co.'s (DIS) Hulu + Live TV. The deal, which grants Fubo investors a 30% stake in the new entity and a $220 million cash settlement, boosted the stock by a staggering 220.6% year-to-date.

2. Oklo Inc. (OKLO)

Oklo is a nuclear energy company developing small fission reactors to supply clean energy. With Big Tech firms prioritizing clean energy for data centers and AI infrastructure, nuclear power stocks have gained significant traction. Oklo, which went public in May 2024, is backed by OpenAI co-founder Sam Altman. Its stock has surged by 96% in the first month of 2025, continuing its strong performance from 2024.

3. Akero Therapeutics Inc. (AKRO)

Akero Therapeutics is a clinical-stage biopharmaceutical company developing treatments for metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. Its lead drug, efruxifermin, showed promising mid-stage clinical trial results in reversing cirrhosis without worsening MASH symptoms. Investors responded positively to the news, and the company raised $400 million through a public offering. The stock surged 94.3% year-to-date.

4. H&E Equipment Services Inc. (HEES)

H&E Equipment provides rental and sales services for construction and industrial equipment. The company’s fleet, valued at $2.9 billion, includes aerial platforms and earthmoving equipment. On January 14, United Rentals Inc. (URI) announced a $4.8 billion acquisition of H&E, offering $92 per share. This news sent the stock soaring 81.1% in 2025, with limited additional upside expected as the stock is already trading near its buyout price.

5. OppFi Inc. (OPFI)

OppFi is a fintech company that connects banks with consumers in need of credit. After going public in 2021 via a SPAC merger, its stock struggled for years. However, in 2025, OppFi’s stock surged to new all-time highs. Analysts believe that the pro-business stance of President Donald Trump's administration could create favorable conditions for the financial sector, further supporting OppFi’s growth. The stock has already risen by 78.9% this year.

6. Agilon Health Inc. (AGL)

Agilon Health is a physician management company focused on providing care through a subscription-like model for Medicare patients. The stock has struggled since its 2021 IPO at $23 per share, trading below $2 at the end of 2024. However, it experienced a significant rally in January, gaining 75.7%, despite no major announcements. This recovery suggests renewed investor interest in the company’s long-term potential.

7. Tempus AI Inc. (TEM)

Tempus AI is a health care technology company leveraging artificial intelligencea to provide advanced diagnostic tools and services. In January, former House Speaker Nancy Pelosi purchased 50 call options for Tempus AI at a $20 strike price, signaling confidence in the company's growth. Shortly after, Tempus AI launched “Olivia,” an AI-powered health concierge app designed to centralize and simplify patient health data. The combination of strong investor backing and product innovation helped drive the stock up by 69.9% in January.

8. Grail Inc. (GRAL)

Grail is a health care company focused on early cancer detection through its multi-cancer early detection (MCED) testing. The company recently reported that its MCED tests cause minimal patient distress, which strengthens its market potential. Having been spun off from Illumina Inc. (ILMN) in June 2024, Grail has gained momentum as a standalone company. Its stock rose from $18.35 at launch to over $30 in January, reflecting a 69.6% increase.

9. Exodus Movement Inc. (EXOD)

Exodus Movement operates a self-custodial cryptocurrency wallet platform, making crypto transactions easier for users. The company moved from the OTCQX exchange to the NYSE American exchange in December 2024, a move that significantly increased its public profile. With growing investor interest in the cryptocurrency sector, Exodus shares surged 62.6% year-to-date, making it one of the strongest performers in the market.

10. Inari Medical Inc. (NARI)

Inari Medical specializes in medical devices used for treating venous diseases. Their key products, the FlowTriever and ClotTriever systems, are leading innovations in the venous thromboembolism (VTE) treatment market. On January 6, Stryker Corp. (SYK) announced its plan to acquire Inari for $4.9 billion, paying $80 per share—a 60% premium over its previous price. The acquisition will bolster Stryker’s position in the growing VTE segment, with the deal expected to close in the first quarter. Given this, Inari’s stock saw an impressive 56% gain in January alone.

FAQ

Q.1. What risks should investors consider before buying these stocks?
A.1. Risks include market volatility, industry competition, regulatory changes, and potential economic downturns.

Q.2. How do mergers and acquisitions impact stock prices?
A.2. Mergers and acquisitions often boost stock prices due to increased market share, financial stability, and strategic growth opportunities.

Q.3. Are these stocks suitable for long-term investment?
A.3. Some may offer long-term growth potential, but investors should analyze financials, industry trends, and company fundamentals.

Q.4. What role does AI play in the stock market’s growth?
A.4. AI-driven innovations are transforming industries, increasing efficiency, and creating investment opportunities in technology, health care, and finance.

Q.5. How can I stay updated on high-performing stocks?
A.5. Follow financial news, track market trends, and use stock analysis tools to stay informed about top-performing stocks.

Conclusion:

The stock market in 2025 has started strong, with several companies experiencing rapid gains due to strategic moves and favorable market trends. While past performance is impressive, investors should conduct thorough research before making investment decisions.

Important Note: Please Read Before You Invest

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